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Wednesday, October 31, 2012
Friday, October 26, 2012
Seminal events in 2012 Alzheimer's disease research evaluated at international conference
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Public release date: 25-Oct-2012[ | E-mail |
Share ] Contact: Virginia Bader
vbader@gymr.com
202-745-5115
GYMR
Genevieve Matthews
gfmatthews@ucsd.edu
858-699-9187
University of California, San Diego
Kimberly Rymsha
krymsha@gymr.com
202-745-5054
GYMR
Global research community presents new findings and sets path for AD drug development
Monte Carlo, Monaco (October 25, 2012) The 5th International Conference on Clinical Trials for Alzheimer's Disease (CTAD) will provide the stage for a closer examination of the unexpected outcomes of Phase 3 treatment trials with some encouraging findings this year the first such results in the Alzheimer's field in almost a decade. The 2012 program will also analyze building evidence that can help focus global research dollars and priorities, namely that detecting AD years, even decades, before clinical symptoms appear offers the best opportunity for current and new drugs to work.
Researchers will also discuss important goals in worldwide AD research, including improving early detection and accurate diagnosis methods, harmonization of imaging techniques across patient populations, identifying factors that affect AD progression, and advancement in AD biomarkers. Chairing the conference are Paul Aisen, MD, University of California at San Diego; Jacques Touchon, MD, University of Montpellier; Bruno Vellas, MD, University of Toulouse; and Michael Weiner, MD, University of California at San Francisco.
Since its debut in Montpellier, France in 2008, CTAD has maintained its unique role in AD research as an intimate professional forum for the world's preeminent clinical researchers to share ideas and foster international collaboration toward progress in a disease that threatens the health of all nations and is soon expected to become the single largest health care expense for many. Alzheimer's is a progressive and ultimately fatal neurodegenerative disease that today affects more than 35 million individuals, robbing them of their memory, independence, and ability to think and understand. By 2050, the number of people with AD is expected to exceed 115 million worldwide if nothing is done to slow or prevent the disease.
"The research presented at CTAD and the very nature of the meeting are critical to creating a clear path for global research in Alzheimer's disease," said Michael W. Weiner, MD, Director, Center for Imaging of Neurodegenerative Diseases at the San Francisco Veterans Affairs Medical Center and co-organizer and a spokesman for the conference. "No one country is going to be able to solve Alzheimer's alone, and we are bringing together the best in the field to spur better discoveries faster."
Research materials will be posted under the CTAD press tab as embargoes lift at: http://www.ctad.fr/12-press/press.asp. Highlights of the CTAD 2012 symposia, oral communications, plenary presentations, and poster sessions include the following:
Solanezumab and Bapineuzumab Trials
Further results from the solanezumab Phase 3 studies will be presented. This includes the release of an analysis of pooled data from solanezumab trials examining AD fluid biomarkers and neuroimaging measures. The solanezumab studies demonstrated cognitive benefits, especially in those with mild dementia. These results, as well as new biomarker data from MRI, CSF, and amyloid PET scan studies in the solanezumab trials, will be presented at CTAD in two symposia.
Safety and Efficacy of Solanezumab in Patients with Mild to Moderate Alzheimers Disease: Results from Phase 3, Rachelle S. Doody, MD, PhD, Baylor College of Medicine - Department of Neurology, Houston, Texas, USA will be held October 29th, 4:30 4:50 p.m.
Update in Clinical Trials [solanezumab] is part of Symposium 5 on October 30th, 11:00 a.m.
While the results from the bapineuzumab Phase 3 studies in mild to moderate Alzheimer's disease patients did not show cognitive or functional benefits, encouraging biomarker data demonstrated a stabilization in the amount of amyloid plaque and an effect on neurodegeneration as indicated by a decrease in CSF phospho-tau protein.
Bapineuzumab IV Phase 3 Results will be presented in Symposium 2 on October 29th, 11:15 a.m. Chairman: Philip Scheltens, VU University Medical Center, Alzheimer Center, Amsterdam, the Netherlands; Presenters: Reisa Sperling, Brigham & Women's Hospital, Boston, MA, USA; Stephen Salloway, MD, Butler Hospital, Providence, RI, USA; Nick Fox, UCL, Institute of Neurology, London, United Kingdom.
Preventing AD with a Multi-Domain Intervention
Researchers from the University of Montpellier and University of Toulouse will present imaging and clinical data from the MAPT trial (MultiDomain Alzheimer's Preventive Trial). MAPT represents the first multidomain preventive trial in AD. The goal of MAPT is to assess whether the combination of physical exercise, cognitive exercise, and nutritional supplementation with omega 3 fatty acids is effective in preventing or slowing cognitive and functional decline.
Preliminary results comparing the intervention subjects with controls suggest some improvement at 6 and 12 months in brain metabolism. These data will be presented in Symposium 7 October 30th, 4:30 p.m.
Presymptomatic Trials: Are We Ready?
Enthusiasm for testing drugs in the presymptomatic phase of the disease is tempered by two major challenges: how to identify and enrich a study with individuals who are cognitively normal but on track to develop AD, and how to assess the ability of a drug to slow the subtle changes that occur in the earliest stages of the disease. Researchers at the University of California, San Diego examined rates of decline in subjects with mild cognitive impairment (MCI) and in elderly subjects who were cognitively normal.
The researchers found that long natural history studies of AD are needed to understand the biomarker changes that precede dementia, and to pinpoint specifically when the biomarkers of currently clinically normal patients start to change rapidly to help measure clinical efficacy of treatment. These data will be presented in session OC14 October 30th, 1:00 p.m.
The same research team has also shown that it may be difficult to distinguish AD from normal aging in the oldest old, since clinical decline and brain atrophy tend to slow with advanced age in individuals with MCI and AD, but speed up in healthy controls. This would indicate that younger cohorts are desirable to detect change, and older people are needed to help confirm how well therapies are tolerated across the age spectrum. These data will be presented in session OC13 October 30th, 8:30 a.m.
Standards that Can Help the Global Field Work More Seamlessly
As AD drug development has increasingly become a global enterprise, there has been growing recognition of the need for standardized protocols to diagnose disease and assess and report treatment effects. Groundbreaking progress has been made by the Alzheimer's Disease Neuroimaging Initiative (ADNI) and its worldwide partners. Building on the success of ADNI, international partnerships have emerged for harmonizing analytical protocols in several areas. Harmonized measurement can facilitate regulatory involvement and approval, and help speed the clinical application of disease-modifying treatments shown to be effective in clinical trials.
Specific efforts that will be featured at CTAD2012 include:
- After four years of work, an international task force has reached consensus on a protocol for measuring brain volume in the hippocampus, an area of the brain associated with memory, which is most affected by neurodegeneration in AD. Once validated, this protocol will enable comparison and comingling of data collected at different sites in clinical trials.
These data will be presented in session OC8 Definition of Harmonized Protocol for Hippocampal Segmentation, October 29th, 3:15 p.m. - A standardized and validated assay has also been developed by Meso Scale Discovery for measuring the levels of two biomarkers in the cerebrospinal fluid CSF that are used to determine if a patient has AD or MCI.
These data will be presented in session OC18 Towards Standardization of CSF Biomarkers: A Multi-Site Study Using Validated Assays for A?42 and Tau, October 30th, 2:00 p.m. - Recognizing that different requirements from regulatory agencies around the world can slow the approval of new treatments for AD, representatives from U.S. and European regulatory agencies and non-profit organizations have joined forces to spur global consensus on regulatory requirements and propose a collaborative mechanism.
These data will be presented in session S1 - Harmonizing Regulatory Requirements to Benefit Future Alzheimer's Disease Patients, October 29th, 8:45 a.m. - The STARDdem (STAndards of Reporting Diagnostic test accuracy, dementia) initiative has developed draft guidelines for authors and editors to use when reporting the results of clinical trials to ensure accuracy and transparency. These guidelines will be discussed at CTAD, prior to being submitted for publication as a consensus statement.
These data will be presented in session 6 Harmonization of Reporting Standards for Studies of Diagnostic Test Accuracy in Dementia: The STARDdem, October 30th, 9:45 a.m.
###
Reporting on all studies is under embargo until the time of presentation. See the full program at www.ctad.fr/.
About CTAD
Since 2008, CTAD has been a conference organized and planned by Alzheimer's disease (AD) clinical researchers for AD clinical researchers. CTAD embraces the organizing committee mandate to maintain CTAD's unique role in AD research: To provide a substantive, clinical research-oriented conference and an annual opportunity for the world's preeminent clinical researchers to engage in both formal and informal exchanges of views. CTAD's ongoing commitment to providing a relatively intimate forum has resulted in the conference's reputation of facilitating and fostering international collaboration in AD clinical research matters. More information is available at www.ctad.fr/.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 25-Oct-2012[ | E-mail |
Share ] Contact: Virginia Bader
vbader@gymr.com
202-745-5115
GYMR
Genevieve Matthews
gfmatthews@ucsd.edu
858-699-9187
University of California, San Diego
Kimberly Rymsha
krymsha@gymr.com
202-745-5054
GYMR
Global research community presents new findings and sets path for AD drug development
Monte Carlo, Monaco (October 25, 2012) The 5th International Conference on Clinical Trials for Alzheimer's Disease (CTAD) will provide the stage for a closer examination of the unexpected outcomes of Phase 3 treatment trials with some encouraging findings this year the first such results in the Alzheimer's field in almost a decade. The 2012 program will also analyze building evidence that can help focus global research dollars and priorities, namely that detecting AD years, even decades, before clinical symptoms appear offers the best opportunity for current and new drugs to work.
Researchers will also discuss important goals in worldwide AD research, including improving early detection and accurate diagnosis methods, harmonization of imaging techniques across patient populations, identifying factors that affect AD progression, and advancement in AD biomarkers. Chairing the conference are Paul Aisen, MD, University of California at San Diego; Jacques Touchon, MD, University of Montpellier; Bruno Vellas, MD, University of Toulouse; and Michael Weiner, MD, University of California at San Francisco.
Since its debut in Montpellier, France in 2008, CTAD has maintained its unique role in AD research as an intimate professional forum for the world's preeminent clinical researchers to share ideas and foster international collaboration toward progress in a disease that threatens the health of all nations and is soon expected to become the single largest health care expense for many. Alzheimer's is a progressive and ultimately fatal neurodegenerative disease that today affects more than 35 million individuals, robbing them of their memory, independence, and ability to think and understand. By 2050, the number of people with AD is expected to exceed 115 million worldwide if nothing is done to slow or prevent the disease.
"The research presented at CTAD and the very nature of the meeting are critical to creating a clear path for global research in Alzheimer's disease," said Michael W. Weiner, MD, Director, Center for Imaging of Neurodegenerative Diseases at the San Francisco Veterans Affairs Medical Center and co-organizer and a spokesman for the conference. "No one country is going to be able to solve Alzheimer's alone, and we are bringing together the best in the field to spur better discoveries faster."
Research materials will be posted under the CTAD press tab as embargoes lift at: http://www.ctad.fr/12-press/press.asp. Highlights of the CTAD 2012 symposia, oral communications, plenary presentations, and poster sessions include the following:
Solanezumab and Bapineuzumab Trials
Further results from the solanezumab Phase 3 studies will be presented. This includes the release of an analysis of pooled data from solanezumab trials examining AD fluid biomarkers and neuroimaging measures. The solanezumab studies demonstrated cognitive benefits, especially in those with mild dementia. These results, as well as new biomarker data from MRI, CSF, and amyloid PET scan studies in the solanezumab trials, will be presented at CTAD in two symposia.
Safety and Efficacy of Solanezumab in Patients with Mild to Moderate Alzheimers Disease: Results from Phase 3, Rachelle S. Doody, MD, PhD, Baylor College of Medicine - Department of Neurology, Houston, Texas, USA will be held October 29th, 4:30 4:50 p.m.
Update in Clinical Trials [solanezumab] is part of Symposium 5 on October 30th, 11:00 a.m.
While the results from the bapineuzumab Phase 3 studies in mild to moderate Alzheimer's disease patients did not show cognitive or functional benefits, encouraging biomarker data demonstrated a stabilization in the amount of amyloid plaque and an effect on neurodegeneration as indicated by a decrease in CSF phospho-tau protein.
Bapineuzumab IV Phase 3 Results will be presented in Symposium 2 on October 29th, 11:15 a.m. Chairman: Philip Scheltens, VU University Medical Center, Alzheimer Center, Amsterdam, the Netherlands; Presenters: Reisa Sperling, Brigham & Women's Hospital, Boston, MA, USA; Stephen Salloway, MD, Butler Hospital, Providence, RI, USA; Nick Fox, UCL, Institute of Neurology, London, United Kingdom.
Preventing AD with a Multi-Domain Intervention
Researchers from the University of Montpellier and University of Toulouse will present imaging and clinical data from the MAPT trial (MultiDomain Alzheimer's Preventive Trial). MAPT represents the first multidomain preventive trial in AD. The goal of MAPT is to assess whether the combination of physical exercise, cognitive exercise, and nutritional supplementation with omega 3 fatty acids is effective in preventing or slowing cognitive and functional decline.
Preliminary results comparing the intervention subjects with controls suggest some improvement at 6 and 12 months in brain metabolism. These data will be presented in Symposium 7 October 30th, 4:30 p.m.
Presymptomatic Trials: Are We Ready?
Enthusiasm for testing drugs in the presymptomatic phase of the disease is tempered by two major challenges: how to identify and enrich a study with individuals who are cognitively normal but on track to develop AD, and how to assess the ability of a drug to slow the subtle changes that occur in the earliest stages of the disease. Researchers at the University of California, San Diego examined rates of decline in subjects with mild cognitive impairment (MCI) and in elderly subjects who were cognitively normal.
The researchers found that long natural history studies of AD are needed to understand the biomarker changes that precede dementia, and to pinpoint specifically when the biomarkers of currently clinically normal patients start to change rapidly to help measure clinical efficacy of treatment. These data will be presented in session OC14 October 30th, 1:00 p.m.
The same research team has also shown that it may be difficult to distinguish AD from normal aging in the oldest old, since clinical decline and brain atrophy tend to slow with advanced age in individuals with MCI and AD, but speed up in healthy controls. This would indicate that younger cohorts are desirable to detect change, and older people are needed to help confirm how well therapies are tolerated across the age spectrum. These data will be presented in session OC13 October 30th, 8:30 a.m.
Standards that Can Help the Global Field Work More Seamlessly
As AD drug development has increasingly become a global enterprise, there has been growing recognition of the need for standardized protocols to diagnose disease and assess and report treatment effects. Groundbreaking progress has been made by the Alzheimer's Disease Neuroimaging Initiative (ADNI) and its worldwide partners. Building on the success of ADNI, international partnerships have emerged for harmonizing analytical protocols in several areas. Harmonized measurement can facilitate regulatory involvement and approval, and help speed the clinical application of disease-modifying treatments shown to be effective in clinical trials.
Specific efforts that will be featured at CTAD2012 include:
- After four years of work, an international task force has reached consensus on a protocol for measuring brain volume in the hippocampus, an area of the brain associated with memory, which is most affected by neurodegeneration in AD. Once validated, this protocol will enable comparison and comingling of data collected at different sites in clinical trials.
These data will be presented in session OC8 Definition of Harmonized Protocol for Hippocampal Segmentation, October 29th, 3:15 p.m. - A standardized and validated assay has also been developed by Meso Scale Discovery for measuring the levels of two biomarkers in the cerebrospinal fluid CSF that are used to determine if a patient has AD or MCI.
These data will be presented in session OC18 Towards Standardization of CSF Biomarkers: A Multi-Site Study Using Validated Assays for A?42 and Tau, October 30th, 2:00 p.m. - Recognizing that different requirements from regulatory agencies around the world can slow the approval of new treatments for AD, representatives from U.S. and European regulatory agencies and non-profit organizations have joined forces to spur global consensus on regulatory requirements and propose a collaborative mechanism.
These data will be presented in session S1 - Harmonizing Regulatory Requirements to Benefit Future Alzheimer's Disease Patients, October 29th, 8:45 a.m. - The STARDdem (STAndards of Reporting Diagnostic test accuracy, dementia) initiative has developed draft guidelines for authors and editors to use when reporting the results of clinical trials to ensure accuracy and transparency. These guidelines will be discussed at CTAD, prior to being submitted for publication as a consensus statement.
These data will be presented in session 6 Harmonization of Reporting Standards for Studies of Diagnostic Test Accuracy in Dementia: The STARDdem, October 30th, 9:45 a.m.
###
Reporting on all studies is under embargo until the time of presentation. See the full program at www.ctad.fr/.
About CTAD
Since 2008, CTAD has been a conference organized and planned by Alzheimer's disease (AD) clinical researchers for AD clinical researchers. CTAD embraces the organizing committee mandate to maintain CTAD's unique role in AD research: To provide a substantive, clinical research-oriented conference and an annual opportunity for the world's preeminent clinical researchers to engage in both formal and informal exchanges of views. CTAD's ongoing commitment to providing a relatively intimate forum has resulted in the conference's reputation of facilitating and fostering international collaboration in AD clinical research matters. More information is available at www.ctad.fr/.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-10/g-sei_1102512.php
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Thursday, October 25, 2012
Solid Advice On Achieving A Fit Body
finding the specific facts you need for your goals can be challenging
Don't lift weights for more than one hour. Your muscles start to deteriorate if you train for more than an hour. You should keep workouts no more than an hour.
Walking your dog can be helpful when you are trying to improve your fitness. Dogs love to be taken for walks and will not tire of walking every day. Remember that you should begin with easy walks. Walk around the block you live on and judge whether or not you're capable of anything more when you are back in front of your house. This is one of the many perks of being a dog owner.
If you want perfect ab muscles, start an aerobic workout. Try doing two or three days worth of weight training and 30 or 45 minutes worth of cardio three times per week. Exercises that target your abs should be done on an alternating schedule with full-body workouts every other day.
It is good practice to exercise outdoors when possible. Dance classes, power walking at the beach or taking a bike ride to somewhere new are all things that could be considered. If your workouts are interesting, you will have an easier time completing them. The fresh air can lower your stress as well and improve your thinking.
You should drink water as often as you can. The more active you are, the faster you dehydrate due to the heat your muscles generate as you move. Your body responds with a cooling system that includes sweating, which may dehydrate you a little bit.
Setting and reaching personal fitness goals is a great way to stay motivated. Having something to focus on can help you avoid obsessing over how hard it is. Having a goal in place will also work to discourage quitting. It will make you focus more on the ongoing process of fitness, and you will know that you are not done yet.
Many people think the only way to get fit is by lifting weights. While lifting weights certainly help you to meet your fitness goals, it's also possible to do simple exercises like push ups and pull ups to reach your goals.
If an exercise ball is something you feel you can securely balance on, it can serve as a terrific substitute for your everyday office chair. Using a stability ball will strengthen your core and create a higher level of balance. Overall, the fitness ball is great because there are many exercises and variations of those exercises that can be done with it.
If you're running sprints, you should want to increase the speed of your running strides. When doing this, make sure your front foot lands under you as opposed to in front of you. In order to better propel yourself, push with the toes of your back leg. With a bit of practice, you will probably see your running speed pick up the pace.
Try running with a friend. When you have a friend to run with, it can benefit you if they are in better physical condition than you. A friend who is good shape can motivate you to want to be more like them. A sense of freindly competition with your running buddy will help you stay motivated to come up to their level.
Experts have conflicting opinions about fitness, and it is therefore a messy subject. Though it can seem daunting, it is possible to narrow it down to specific things that are necessary, and others to definitely avoid. Read this article for some tips on simple life changes that will allow you to become more fit.
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Obama On Marathon Tour; Romney Runs ... - Yeshiva World News
A scratchy-voiced President Barack Obama powered through a marathon drive to get his supporters to vote Thursday and planned to set an example by becoming the first president to cast his own ballot ahead of time. Republican Mitt Romney spent one of the precious 12 days before Election Day entirely focused on the Rust Belt battleground of Ohio.
With a new Associated Press-GfK poll showing Romney has erased Obama?s 16-point advantage among women, the president tried to keep a GOP abortion controversy alive. Obama repeatedly made a veiled reference to Indiana Senate candidate Richard Mourdock?s comment that pregnancies resulting from rape are ?something God intended.?
?We?ve seen again this week, I don?t think any male politicians should be making health care decisions for women,? Obama said. His campaign also has been intensifying its criticism of Romney for refusing to pull his support for Mourdock, even though the Republican presidential nominee said he disagrees with Mourdock?s comment.
Romney tried to avoid the subject. While picking up breakfast at a downtown Cincinnati diner on Thursday, Romney refused to answer repeated questions from reporters standing nearby about Mourdock?s comment and whether he would call for Mourdock to take down a TV ad Romney filmed for him earlier this week.
At a rally later at the Jet Machine manufacturing company, Romney didn?t mention anything about abortion but spoke repeatedly about the choices facing American families. He said seniors on Medicare would struggle to find doctors if Obama is re-elected, daughters would face crushing college loan debt and parents would lose choices about where to educate their children.
?This election is not about me. It?s not about the Republican Party,? Romney told a crowd estimated at 3,000. ?It?s about America. And it?s about your family.?
Romney?s campaign reached out to women by sending Ann Romney on daytime?s ?Rachael Ray? show, where she prepared her meatloaf cakes recipe and took cameras along on a trip to Costco to shop in bulk for family gatherings. Mrs. Romney said that, with 30 mouths to feed, her family always eats buffet-style and that ?Mitt is often at the front of the line.?
Romney was on a daylong swing through three Ohio towns, sharpening his focus on a state critical to his hopes of winning the White House. The Republican?s advisers say their internal data has him tied to win the state?s 18 Electoral College votes, but public polling has shown Obama with a slim lead.
Obama, in the midst of a four-state blitz on Thursday, also was scheduled to finish his day in Ohio. Shortly after Romney concludes his evening remarks in Defiance, the president was set to appear 150 miles to the east in Cleveland.
Virginia also got attention from both campaigns on an unseasonably warm October day, with Obama drawing a massive crowd estimated at 15,000 to Richmond?s Byrd Park while GOP vice presidential nominee Paul Ryan spoke before a smaller group at the opposite end of the state in Appalachian coal country. Ryan told the audience of about 1,500 that winning a close race won?t be enough for the GOP ticket.
?The worst thing that could happen is President Obama gets re-elected and we have more of the same with a debt crisis,? Ryan said. ?The second worst thing that could happen is we get elected by default, without a mandate.?
The AP-GfK poll released Thursday shows the presidential race still a virtual dead heat nationally, with Romney favored by 47 percent of likely voters and Obama by 45 percent. That result is within the poll?s 4.2-point margin of error.
Although national polls show the race is close, Romney is struggling to overtake Obama in the state-by-state march to racking up the 270 Electoral College votes needed for victory. Romney has far fewer paths to reaching that threshold than Obama, who starts with more states ? and more Electoral College votes ? in his win column. The race is centered on just nine states, where polls show competitive races: Ohio, Florida, Iowa, New Hampshire, Virginia, North Carolina, Colorado, Nevada and Wisconsin.
The president?s morning rally kicked off the second day of his 40-hour battleground state blitz. Shortly after 7 a.m. and less than five hours after ending his day in Las Vegas, Obama was at a Krispy Kreme doughnut shop near downtown Tampa, and minutes later delivered the still warm doughnuts to a nearby firehouse. He said he wanted to come by early ? noting he is not often out this early ? to thank them for all they do.
Obama then spoke to about 8,500 people at a morning rally in Tampa, a swing area of battleground state Florida. With a full day of campaigning still ahead of him, Obama?s voice was already hoarse. But he told the enthusiastic crowd he was ?just going to keep on keeping on until every single person out there who needs to vote is going to go vote.?
He noted to cheers that he was going to Chicago later Thursday to participate in early voting and that first lady Michelle Obama already mailed in her ballot. Obama campaign spokesman Jennifer Psaki said they hoped his example would send a message to others in early voting states that they should do so as well.
About 7.2 million people have already cast early ballots, either by mail or in person, according to the United States Elections Project at George Mason University. In all, about 35 percent of the electorate is expected to vote before Election Day, a small increase over 2008.
Obama?s campaign also announced joint rallies Monday with Bill Clinton in Orlando, Fla., Youngstown, Ohio, and Prince William County, Va. The president also picked up an endorsement from former Secretary of State Colin Powell, a Republican who supported Obama in 2008. Powell praised Obama?s handling of the economic recovery, telling ?CBS This Morning:? ?I think we?ve begun to come out of the dive and we?re gaining altitude.? Obama told his Virginia audience that he was ?proud and humbled? to get Powell?s support.
(AP)
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Source: http://www.theyeshivaworld.com/?p=142566
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Why New Federal Rules for Debt Collectors Don't ... - Yahoo! Finance
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From credit cards to mortgages to student loans, the average American consumer is loaded with debt. Roughly 30 million people have debt collection agencies coming after them to repay an average of $1,500 in unpaid loans.
For the first time ever, Americans will be somewhat more protected from the sometimes aggressive practices of debt collectors.
Related: Obama's Student Loan Program Is a Windfall for the Rich Study Says
The Consumer Financial Protection Bureau announced Wednesday that it will supervise debt collection agencies with more than $10 million in annual receipts and release a field guide that will be used by its examiners.
"Millions of consumers are affected by debt collection, and we want to make sure they are treated fairly," said CFPB Director Richard Cordray in a press release. "We want all companies to realize that the better business choice is to follow the law ? not break it."
According the The New York Times, The Federal Trade Commission, which collects and enforces abusive practices by credit agencies, collected 180,000 consumer complaints about debt collection agencies in 2011, up from about 14,000 in 2000.
The new CFPB rules are set to take effect on Jan. 2, 2013 and will impact about 175 of the 4,500 debt collection agencies in the country. While that number may seem small, the newly regulated debt collectors account for more than 60% of the industry's $12 billion in annual collections.
Next year the consumer watchdog will make sure that debt collectors are following the proper practices and procedures when contacting consumers. Collection agencies must adequately identify themselves and then indicate the amount to which they are seeking collection. Additionally, there must be a sound method for settling disputes "civilly and honestly" with consumers.
"Examiners will be assessing whether debt collectors have harassed or deceived consumers in pursuit of debt," said the CFPB in a statement. "For example, debt collectors should not be using obscene or profane language with consumers. Nor should they be engaging the consumer in telephone conversations repeatedly or continuously with intent to annoy, abuse, or harass. Debt collectors cannot threaten to imprison consumers who do not pay their debt or threaten to tell the consumer's employer about the debt."
Roughly one-third of states allow delinquent borrowers to be thrown in jail, according to The Wall Street Journal.
Related: THE RETURN OF DEBTORS PRISONS: Collection Agencies Now Want Deadbeats Arrested
"As the CFPB is a work in progress so are these rules. The Fair Debt Collection Practices Act is antiquated and needs a refresh to bring it into the 21st Century," says Adam Levin, chairman and co-Founder of Credit.com in an e-mail to The Daily Ticker. In that same vein,Aaron Task and Henry Blodget discuss in the accompanying video why there should be one set of bankruptcy laws for people and corporations.
"I think the $10 million threshold is too high, I agree with many consumer advocates that the zone of regulation should be expanded and the regulatory entry point should be lowered to $7 million as it is proposed for credit reporting agencies. That will cover many smaller collectors who are more problematic than many of the larger collectors," says Levin. "With the evolution of technology from robo-calling, smart phones, texts and social networking, the little shop can now play in the bigger debt collection leagues and harass and intimidate consumers which equal effectiveness and even less regard for consumer protection. We need to put the spotlight on the entire community to ensure that consumers and legitimate collectors are protected from bad actors."
The CFPB is set to hold a public field hearing today at 1 pm ET to release the new rules. The hearing will be webcast on the watchdog's website.
Tell us what you think!
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Wednesday, October 24, 2012
EU sends Microsoft formal antitrust complaint
BRUSSELS The European Union's executive arm formally accused Microsoft (MSFT) on Wednesday of failing to comply with a binding agreement to give customers a choice among Internet browsers.
In 2009, the European Commission said it suspected Microsoft of using its dominant market position to foist its Internet Explorer browser on users. In negotiations, Microsoft agreed to create a screen where users could choose among competitors' browsers. The Commission accepted that concession and made the creation of a "browser choice screen" legally binding.
But in July, the Commission said the screen had not been displayed on many computers between February 2009 and July 2012, and millions of users may have been affected during that period. At the time, Microsoft said that a technical error was responsible.
EU Competition Commissioner Joaquin Almunia said any breach would be a "serious infringement," noting that the settlement between the EU and Microsoft had allowed the company to avoid lengthy antitrust proceedings and being held liable.
"Companies should be deterred from any temptation to renege on their promises or even to neglect their duties," he said.
On Wednesday, the company apologized for the error and said it was working to make sure it didn't happen again,
"We take this matter very seriously and moved quickly to address this problem as soon as we became aware of it," Microsoft said in a statement. "Although this was the result of a technical error, we take responsibility for what happened."
Microsoft will now be given four weeks to respond to the formal complaint and can seek an oral hearing. Once it has assessed Microsoft's defense, the Commission will rule.
The company could face a fine of up to 10 percent of its annual revenue if found in breach of antitrust law.
Source: http://feeds.cbsnews.com/~r/CBSNewsBusiness/~3/0EiYQrFagaM/
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Union: Ford to close Belgian plant in 2014
By RAF CASERT
Associated Press
Associated Press
BRUSSELS (AP) - A union leader said Wednesday Ford Motor Co. has decided to close one of its main factories in eastern Belgium by the end of 2014 in a move that will result in 4,500 direct job losses and 5,000 more among subcontractors.
Exactly half a century after construction on the Genk plant started, local Ford management read a letter announcing the move at a specially called council , Christian Democrat union representative Johan Lamers said.
"This is taking us by surprise and is an extremely bitter pill," Lamers told the Associated Press.
Ford Motor Co. has been under pressure in Europe due to the region's dwindling demand for its cars and reflects the overall slide of car sales in Europe.
The plant in Genk makes the midsize Mondeo and the S-MAX minivan. The company expects to lose more than $1 billion this year in Europe, where it gets a quarter of its sales. Analysts say the company has more factory capacity than it needs.
Lamers said the production of the Mondeo will move to Valencia, Spain.
Ford has been struggling in Europe. Figures from Acea, the European carmakers' association, show an overall slide of sales for the European market of 10.8 percent on a year-by-year basis in September. Meanwhile, Ford's drop in sales was 14.9 percent.
Ford's European management was expected to meet with Belgian Prime Minister Elio Di Rupo and regional Flemish authorities later Wednesday.
The announcement came barely a month after Ford had given reassurances about production at the Genk plant, Lamers said.
Ford Genk represents more than 30 percent of car production in Belgium.
Workers took the announcement early Wednesday with relative calm. A fire was set up at the gate of the plant but there was little action - especially since the factory was in the middle of a three-week layoff because of slack demand.
Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Source: http://www.wistv.com/story/19898859/union-ford-to-close-belgian-plant-in-2014
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Sony Xperia Go arriving in Canada this November
The mid-range waterproof Sony Xperia Go will be coming to Canada by way of Rogers-owned Fido this November. Sony also announced that a snazzy exclusive yellow model available if you're picking one up unlocked from Sony stores, while Fido will have black and white versions available.
The Xperia Go was originally announced running Gingerbread, but an upgrade to Ice Cream Sandwich was rolled out a few weeks ago. Who knows if it'll be lucky enough to get Jelly Bean, but it seems like the real selling point for the Xperia Go is its ruggedness. We've seen this thing take a fair bit of punishment, and if it can keep the pricetag relatively low, there may be a lot of value there. Unfortunately, Sony stayed mum on how much it would cost either on Fido or unlocked, but the UK launch over the summer should provide a good idea of what to expect.
Specs and additional details are in the press release below. Any Fido customers considering picking this one up?
 |  |
Source: http://feedproxy.google.com/~r/androidcentral/~3/Gvh2h-sOTyk/story01.htm
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Tuesday, October 23, 2012
Health News - Increased use of colonoscopy screening could ...
BY JESSICA SHUGART - Use of colonoscopy for colorectal cancer screening could explain a significant decrease in the cancer?s incidence over the past decade, according to a new study from researchers at the Stanford University School of Medicine.
Uri Ladabaum
Although colonoscopy is now the most common colorectal cancer screening method, there has been conflicting evidence as to its effectiveness compared with sigmoidoscopy, a method that examines only a portion of the colon.
The team scrutinized data collected from more than 2 million patients over the past 20 years, and found that a drop in colorectal cancer incidence correlated with Medicare?s extension of colonoscopy coverage in 2001.
?Widespread colonoscopy screening may actually be having an impact in the risk of colon cancer at the level of the general population,? said Uri Ladabaum, MD, MS, associate professor of gastroenterology and hepatology and senior investigator for the study. The results were published online Oct. 23 in Gastroenterology.
Colorectal cancer is the second-leading cause of cancer-related deaths in the United States, according to the federal Centers for Disease Control and Prevention. The American Cancer Society and other groups recommend colorectal cancer screening for people at average risk beginning at age 50. Colonoscopies are recommended once every 10 years for average-risk adults, and more often in those found to have precancerous lesions known as polyps.
Several methods are currently available for the screening. Less-invasive methods, such as stool sample analysis, cause minimal discomfort but some patients consider them a hassle, and the tests need to be performed regularly to be effective. And although these methods occasionally detect precancerous polyps, their primary purpose is detecting early stage cancers.
Colonoscopy and sigmoidoscopy are endoscopic screening methods used both for early cancer detection and for precancerous polyp removal. Sigmoidoscopy only extends into the lower (or distal) part of the colorectum, while colonoscopy extends beyond the lower colorectum and into the upper (or proximal) colon. Although sigmoidoscopy has demonstrated clear benefits in preventing cancers in the lower colorectum, U.S. doctors have increasingly relied on colonoscopy and have made it the most common method of colon cancer screening.
?The faith for a long time has been that looking more deeply into the colon must be better because we?re looking at more of the colon,? said Ladabaum. Despite the presumed benefits of colonoscopy, the actual superiority of the procedure as
compared with sigmoidoscopy has been the subject of conflicting studies.
With the hope of shedding some light on this murky issue, Ladabaum?s team examined available data on the surgery rates for colorectal cancer, and interpreted these in light of the dramatic rise in the use of colonoscopy that began more than a decade ago. The researchers analyzed data from more than 2 million patients collected from the Nationwide Inpatient Sample, a large database that includes more than 1,000 hospitals. Ladabaum and colleagues looked for trends in colorectal cancer surgery, which reflect cancer incidence. They also specifically looked for differences in rates of cancer in the lower versus the upper colon, as colonoscopy is hoped to have a benefit in preventing cancers in both areas due to its extended reach.
The results of the study suggest that increased use of colonoscopy may explain the decrease in incidence of upper colon cancer ? through the identification, and removal, of precancerous polyps ? in the last decade. The overall rate for removing, or resecting, colorectal cancer dropped from 71.1 to 47.3 per 100,000 persons between 1993 and 2009. Resection rates for lower colorectal cancer decreased gradually (at a rate of about 1.2 percent per year) from 1993 to 1999, and then dropped more steeply (to a rate of 3.8 percent per year) from 1999 to 2009. In contrast, the resection rate for upper colon cancer remained steady until 2002, and then started dropping at a rate of 3.1 percent per year until 2009.
These results support the idea that the drop in the incidence of lower colorectal cancer might be associated with screening in general, since some patients were already undergoing stool tests and sigmoidoscopy in the early 1990s, whereas the reduction in upper colon cancer incidence might be specifically associated with colonoscopy, Ladabaum said.
Interestingly, the drop in upper colon cancer incidence was seen not only for people within the suggested screening ages, but also for those over age 75. Currently, there is no consensus on whether to screen people older than 75, Ladabaum said. While some of these older patients may opt to get colonoscopies, he said he thinks these results could mean that colonoscopy screening at an earlier age prevents colorectal cancer later in life.
The availability of a screening technique that effectively detects and removes precancerous lesions makes colorectal cancer a uniquely preventable cancer, he added. ?We really do have an opportunity to find the pre-cancers, before there is even a cancer there,? said Ladabaum.
The study?s first author is Parvathi Myer, MD, a former postdoctoral scholar at Stanford. Other co-authors are research associate Ajitha Mannalithara, PhD, and adjunct professor Gurkirpal Singh, MD.
The study was funded by the National Institutes of Health. Information about Stanford's Department of Medicine, which also supported the work, is available at http://medicine.stanford.edu.
Jessica Shugart is a science-writing intern for the medical school's Office of Communication & Public Affairs.
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Italian earthquake case is no anti-science witch-hunt
Manslaughter verdicts for six seismologists highlight the need for scientists to speak for themselves
It is easy to feel outrage at the jail terms handed down to six Italian seismologists and a civil servant this week. How could anyone hope to have predicted the earthquake that devastated L'Aquila in 2009?
That is the rallying cry, but failure to predict the quake is not, in fact, what the seven men have been convicted of. The prosecution made it crystal clear all along that their case was about poor risk communication; it was built on an accusation of giving out "inexact, incomplete and contradictory information".
On this charge, there was clearly a case to answer. Employed by Italy's Major Hazards Committee to assess earthquake risks and communicate them to the government and the public, the seismologists got the science right, but left the job of public communication to a civil protection official with no specialist knowledge of seismology. His statement to the press was, to put it mildly, a grossly inaccurate reflection of the situation: "The scientific community tells us there is no danger, because there is an ongoing discharge of energy. The situation looks favourable." At this point, the seismologists should have stepped in. But they did not, and the message stuck.
Of course, it is debatable whether this neglect merits a manslaughter conviction and six-year jail term. That is a matter for the Italian justice system. The appeals have already started.
But there are broader issues to consider. Many commentators argue that the L'Aquila verdict will have a chilling effect on the provision of scientific advice in Italy and beyond. That is clearly a concern worth taking seriously.
However, it should also encourage scientists who take on those roles to think long and hard about the responsibilities that come with them. It is tempting for scientists to defer communication with the public to others who are supposedly "experts" in doing so. But this approach often leads to confusion, as evidenced by a litany of failures in the past: BSE, vaccines, genetically modified crops and many more.
This cannot continue. Scientists valued for their expertise should speak for themselves rather than letting others speak for them. Lives are at stake.
If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.
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Recording Your Calls for Sales Training and Self-Improvement Call ...
Recording Your Calls for Sales Training and Self-Improvement Call ?
We have touched on this before?using call recording as a sales training tool. Recently an author over at OC Metro posted a short article about sales training ?
See all stories on this topic ?
Insurance Sales Training!! $25!!
Have you considered a career in the insurance industry? Security of income! Insurance Agencies are ALWAYS looking for new agents!!!! Don't believe me? Try it ?
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Sales Development Manager Programme (Outstation) ? UAE National
? join our Sales Development Manager Programme; the programme's core aim is to provide a structured training programme to develop, train and coach talented Emiratis in all aspects of sales management, leadership and management skills to prepare them ?
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Source: http://masterattractionmarketing.net/?p=10280
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Monday, October 22, 2012
'Elbow test' may predict sleep apnea
Public release date: 22-Oct-2012[ | E-mail |
Share ] Contact: Jennifer Stawarz
jstawarz@chestnet.org
847-498-8306
American College of Chest Physicians
Have you ever been "elbowed" by your bed partner because you were snoring? If yes, new research says you could have obstructive sleep apnea (OSA). Prior to polysomnography testing, researchers from the University of Saskatchewan asked 124 patients two questions: (1) Does your bed-partner ever poke or elbow you because you are snoring; and (2) Does your bed-partner ever poke or elbow you because you have stopped breathing? Answering 'yes' to being awakened for snoring or apneic spells increased the likelihood of an apnea-hypopnea index (AHI) >5/h (indicating at least mild OSA) compared with 'no.' Analysis also showed that as disease severity increased, patients were more likely to be awakened for snoring and apneic spells. Researchers conclude that asking these two simple questions could significantly improve the pretest prediction of a diagnosis of OSA. This study was presented during CHEST 2012, the annual meeting of the American College of Chest Physicians, held October 20 25, in Atlanta, Georgia.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-10/acoc-tm101812.php
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Tucker Varsity Cheerleaders Win First Trophy - Tucker, GA Patch
The Tucker High School varsity football and competition cheerleaders recently won third place at the Kell Stockyard Round-Up Cheering Championship held at Kell High School's Performing Arts Center in Marietta.
Tori Taylor also took home first place in the jump off segment with a big pike and toe touch maneuver.
This is Tucker's first trophy for cheerleading.
The cheerleaders' next event will be the regional competition at Loganville High School on Nov. 3.
Source: http://tucker.patch.com/articles/tucker-varsity-cheerleaders-win-first-trophy
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Shop off-season for major home improvements | Farm and Dairy ...
?
NEW YORK ? An often overlooked side-effect of the recession is that many people cannot afford to move and have decided to stick with the home they have and make desired improvements.
Thanks to off-season discounts, some months of the year may be better than others for renovations. The home improvement industry is not much different than any other. When demand is high, prices are generally at their peak. When demand is low, prices are lowered to entice shoppers to buy.
Shop smart
Right now, many homeowners may be thinking of certain improvements, such as the installation of a pool or deck, or even replacing an air conditioning system in advance of the warm weather. But it could be financially savvy to wait until the warm weather is gone to do so.
Many pool companies and stores discount their inventory considerably after September. That?s because this time of year in most of the country is when the weather starts to change and people are less likely to think about a dip in the pool
Furthermore, in an effort to capitalize on both the summer and winter seasons, many pool stores double as Christmas tree and accessory outlets come the colder months. That means they?ll need to clear out their showrooms and stock areas of pools prior to delivery of Christmas merchandise. You may land a considerable discount on the pool package.
Plus, if you have room in a garage or shed to store the pool equipment and assembled materials, you can wait until the next season to hire an installer to set up the pool when you desire.
Hot and cold
As you are thinking about turning down the thermostat and enjoying a blast of cool air-conditioning, it might be wise to think about the performance of your furnace, too. While HVAC professionals and home improvement chains could be charging top dollar for a new air conditioning system, they may offer discounts on furnaces because they?re simply not in demand this time of year.
If you find an affordable furnace, store the furnace until the time is right to have it installed.
Remodel in late December. The holiday season tends to be a slow time for home-improvement contractors simply because most homeowners are thinking more about shopping and entertaining than knock-down, tear-out jobs. Waiting until the end of the year for some major renovations could be advantageous.
The spring and summer are prime times for outdoor entertaining, so the addition of decks or elaborate landscaping may come at an elevated price. However, once autumn arrives, the same services may be much cheaper, depending on the job and if the contractor can secure materials at a discounted price.
If you can hold off on that new deck or patio until after September, it may be in your best interest. However, if a winter installation is in your design, you may find yourself actually paying more in labor costs if inclement weather delays the installation.
Other tips
Explore wintertime reductions on air conditioning systems.
New appliance models released could mean year-end reductions on that model year.
Purchase bulk topsoil and other landscaping materials in the winter when this industry is slow.
Many pests enter a dormancy during the winter, so exterminators may discount for termite reduction during the winter and early spring.
Fireplace installation or chimney masonry work could be discounted during the summer months.
The spring season is an ideal time for roofing projects, although some contractors will work in the winter, too. Roofing companies are often tied up during the summer months and may ask for premium charges.
Keep in mind that summer is a prime time for any and all improvements. Beat the prices and the wait time by shopping off-season for your renovations.
Related Stories
Source: http://www.farmanddairy.com/news/shop-off-season-for-major-home-improvements/43361.html
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Sunday, October 21, 2012
Palestinian elections: Despite Hamas boycott, Fatah fares poorly
The results announced today add to mounting concerns that Fatah ? and the broader Palestinian leadership ? is losing its legitimacy.
Palestinian President Mahmoud Abbas shows his ink-stained finger after casting his vote during local elections at a polling station in the West Bank city of Ramallah, Saturday. Palestinians voted for mayors and local councils in 93 communities across the West Bank on Saturday, their first chance to cast ballots in six years.
Majdi Mohammed/AP
EnlargeJerusalem; and Ramallah, West Bank
Palestinian Authority President Mahmoud Abbas's Fatah party made a disappointing showing in yesterday's local elections, with its chosen candidates failing to secure local majorities in key cities including Ramallah despite a?boycott by its chief rival, Hamas.?
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?This is a landmark of the end of Fatah,? says Mahdi Abdul-Hadi, head of the Palestinian Academic Society for the Study of International Affairs (PASSIA).
?In the absence of Hamas ? Fatah could not lead completely as expected,? he says,?pointing to the northern city of Nablus where the official Fatah list got only five of 15 available seats, losing the rest to Fatah independents. ?There was no consensus, no leadership coherence, no commitment for the movement.?
The Associated Press cited preliminary results showing Fatah failed to receive majorities in 5 of 11 major towns.?
The results add to mounting concerns about Fatah ? and the broader Palestinian leadership ? losing its legitimacy. PA President Abbas, who doubles as Fatah chairman, has been unable to secure progress on a variety of fronts, from peace talks with Israel, to reconciliation with Hamas, to last year's membership bid at the United Nations, to an economic crisis that has once again delayed payday for Palestinian Authority employees ? all of whom are still waiting to be paid for September.
Stepping stone to national elections
Municipal elections, the first in at least six years, were seen as a potential way to boost the PA's credibility and create momentum for national elections ? badly needed to restore the Palestinian legislature after a split five years ago with Hamas, the Islamist movement that has governed the coastal Gaza Strip ever since.
?I think that a lot of people across the political spectrum are hoping and working to use these elections as a starting point toward national elections and to pressure Hamas ? to conform with the will of the majority of the people to have the national elections as soon as possible,? says Qais Abdul-Karim, a veteran politician and member of the Democratic Front for the Liberation of Palestine.
Mr. Abdul-Karim says overall the elections strengthened the Palestinian political system, but argues that time is running short for nationwide elections ? and that there is growing support among decisionmakers in the Palestine Liberation Organization (PLO) for holding such elections even if Hamas threatens to boycott them as well.
?In my opinion, the time that we have got is very narrow,? he says. ?I think that there is an urgent need for the political system to renovate ? its legitimacy through [national] elections.?
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How not to reinvent the wheel: Five automotive tech flops | Digital ...
Cars have made great technological strides over the past 100 years, but not without a few missteps.
Technology is a wonderful thing, especially when it comes to cars. We wouldn?t have gotten from Daimler and Benz?s three-wheeled, one horsepower wagon to the Bugatti Veyron or Chevy Volt without finding new ways of making things work. However, just because an idea is new, or technically possible, that doesn?t mean it is good or practical. Here are five automotive technological dead ends.
Steering without a wheel: The Benz Patent-Motorwagen is generally considered to be the first automobile, and it was steered with a tiller instead of a steering wheel. It may have been Gottlieb Daimler and Karl Benz?s first idea, but a tiller is much better for controlling a ship?s rudder than a car?s steering mechanism.
Nonetheless, carmakers have continued to experiment with different types of steering. The designers of the Baker and Detroit electric cars (built in the early 1900s) used tillers, but not because they hadn?t been able to test drive the Benz. Rather, their decision was based on marketing.
Electric cars were marketed to women, primarily because their husbands didn?t want them driving too far unescorted, and the cars had pitiful ranges. The manufacturers were on the same page: They felt that the thing women loved doing most was socializing, not driving, so they arranged their car?s interiors like a lounge. Tiller steering allowed the female driver to face her passengers.
Alternative steering didn?t die with women?s liberation. Saab, the car company that was ?Born From Jets,? made a prototype with joystick steering in the early 1990s. The Honda EV-STER concept is also steered with sticks. Still, it seems like wheels are the best way to steer earthbound vehicles.
Pop-out windshield: Preston Tucker?s stillborn car was way ahead of its time. It featured a headlight that turned with the steering wheel, a padded dashboard, and structural reinforcements that were supposed to make it very safe. Not every idea was a winner, though.
The Tucker also featured a windshield that was designed to pop out of its frame in a crash, protecting occupants from glass shrapnel. Unfortunately, the car was never mass-produced; an SEC investigation and the subsequent unraveling of Tucker?s finances became the subject of the film Tucker: The Man and His Dream. The widespread use of shatter-proof laminated glass in car windshields made Tucker?s pop-out windshield unnecessary anyway.
Four-wheel steering: Anyone who has used an Ikea shopping cart knows that allowing the rear wheels to turn can really help maneuverability. Four-wheel steering is actually well within carmakers? technical ability, it just hasn?t caught on.
There has been no shortage of cars with four-wheel steering. Honda equipped the 1987 Prelude with four-wheel steering, and it became a must-have feature on the high-tech Japanese sports cars of the 1990s. The Mitsubishi 3000 GT, Nissan Skyline GT-R R33 and R34, and the Nissan 300ZX all had it.
GMC also offered four-wheel steering on its Sierra Denali full-size pickup truck from 2002 to 2004.
So why doesn?t every car have four-wheel steering? Probably for the same reason most cars do not have four-wheel drive, despite the extra traction it offers. Adding hardware to steer the rear wheels adds complexity, and cost, to a vehicle. People might not want to pay extra for systems that, admittedly, offer less of a concrete benefit than one might think.
Car companies haven?t given up on the idea, though. Acura will include four-wheel steering on the base, front-wheel drive version of its upcoming RLX sedan.
Steam power: Steam trains powered America?s first transportation revolution, so it?s not surprising that early carmakers such as Stanley, White, and Doble put serious effort into selling steam powered automobiles.
These cars worked the same way steam locomotives do. Water was heated in a boiler (usually by burning kerosene) to create steam, which pushed a piston connected to the car?s wheels.
Steam had some advantages over internal combustion. Steam engines didn?t reek of gasoline, and didn?t need to be cranked to get them started. Most importantly, steam was a familiar technology; in the 1900s it was viewed the same way gasoline is viewed today when compared to hybrids.
However, steam had far more drawbacks than anything else. Steam cars may not have needed a crank handle, but they took a long time to get going. Imagine waiting for a giant tea kettle to boil every day before your morning commute, and you?ll get the idea.
Since most steam cars had no electrical accessories, every part of the complicated starting process, from pumping fuel to opening valves to regulate pressure, had to be done manually.
Steam cars also had to be driven carefully, too. Range was dependent on the amount of water in the tank, so it varied with ambient temperature. Drivers would also have to coast whenever possible to build up a head of steam. Maybe today?s fluctuating gas prices aren?t so bad.
Jet power: Carmakers love to make their products look like jet planes, so why not use the same engines? Who cares about tail fins when you can throttle up an actual jet?
Chrysler decided to try building jet powered car in 1963, when it commissioned Ghia to build 55 bodies to house these futuristic powertrains. The Chrysler Turbine Cars were then leased to customers for evaluation, just like 21st century EVs and fuel-cell vehicles.
The Turbine Car was an impressive machine. It idled at 8,000 rpm, above the redline of most piston-engined cars, and could do 0 to 60 mph in 5.5 seconds. It could also run on any flammable liquid, from perfume to tequila.
It may sound like the silver bullet of alternative powertrains, but the jet engine simply isn?t meant for automotive use. Jets are not as responsive as piston engines; drivers of the Chrysler would notice significant lag during acceleration. Mashing the throttle actually made the car go slower, it simply could not be rushed.
Jets may also be too exotic for the road. The Turbine?s performance was impressive, but a Chrysler equipped with a relatively small 318-cubic inch V8 could match it. Jaguar thought about using micro gas turbines to generate electricity in its C-X75 supercar, but it has switched to a 1.6-liter gasoline inline-four, which can apparently do the job just as well.
Source: http://www.digitaltrends.com/cars/five-automotive-tech-flops/
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Saturday, October 20, 2012
Fox extends its primetime due to "X Factor" snafu
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Source: http://news.yahoo.com/fox-extends-primetime-due-x-factor-snafu-212914976.html
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